We are hiring!
The Naba lab welcomes Asia Paguntalan, visiting research specialist, who will contribute to the matrisome project and the human ECM atlas project
The Naba lab wins the 2023 Physiology pumpkin carving contest!
Leanna wins second place in the short talk category at the 2023 GEMS symposium!
Dharma is short-listed to compete for the 2023 Iozzo Post-doctoral Trainee Award
Leanna is selected to give a short talk at the ASMB meeting
Nandini receives an Honors College travel grant to attend the ASMB meeting
Alexandra is speaking at the symposium celebrating the 50th anniversary of the discovery of fibronectin
Nandini receives a LASURI award!
Clarissa delivers the student address at the UIC Honors College convocation!
Nandini receives an Honors College Undergraduate Research Grant!
Fred Lee, MD/PhD student in the lab, successfully defended his PhD!
Ikram receives a Chancellor’s Undergraduate Research Award!
Dharma received a travel grant from Disease Models and Mechanisms
Alexandra is invited to speak at the National Cancer Institute's workshop on "The Landscape of Post-Translational Modifications in Tumor Biology Meeting"
Alexandra is invited to speak at the 2022 Midwest tumor microenvironment meeting
5/23/2022: Alexandra will present the latest work from the lab focused on the "computational and experimental profiling of the mutational landscape of the cancer matrisome" at the 2022 Midwest Tumor Microenvironment Meeting. More information on the meeting can be found here: https://www.kumc.edu/midwesttme.html.
5/6/2022: Anna Barqué received her PhD from the Graduate Education in Biomedical Science program during the commencement ceremony of the UIC College of Medicine. Congratulations Anna! Scroll to 1:51:45 to see Anna receive her hood!
5/4/2022: Ali Thahab, undergraduate research assistant in the lab, graduated summa cum laude from the UIC Honors College. Congratulations Ali! Scroll to 1:39:19 to see Ali receive his gold stole!
Congratulations Fred and Anna!
The 32nd Physiology Awards Night that took place on March 31st, 2022 brought a lot of excitement for our lab! Fred Lee (G3, MSTP) received the 2021 John and Kathy Solaro Endowed Graduate Fellowship and Anna Barqué (G5, GEMS), the Mark R Lambrecht Award for Scholarship and Commitment. Congratulations, Fred and Anna!
Alexandra received a HOPE award!
Clarissa will present her work at the 2022 UIC Undergraduate Research Forum
Clarissa will present her work in collaboration with Pam Kreeger's lab (U. Wisconsin, Madison) on the role of the ECM during high-grade serous ovarian cancer progression at the 2022 UIC Undergraduate Research Forum. Clarissa's work in the lab was supported by a UIC Honors College Research Grant, a LASURI grant, and funding from the UIC Summer Research Opportunities Program (SROP) and Graduate Pathways to Success (GPS) program.
Congratulations Dr. Barqué!
Our lab is excited to announce that Anna Barqué successfully defended her Ph.D thesis entitled "The Extracellular Matrix Protein SNED1 Regulates Neural Crest Cell Phenotype and Carniofacial Development". Congratulations, Dr. Barqué!
In September 2021, the American Society for Matrix Biology (ASMB) organized a hybrid scientific meeting, integrating in-person and virtual formats, to discuss the latest developments in ECM research. In this meeting report written by the Outreach committee of the ASMB chaired by Dr. Naba, we highlight exciting scientific advances that emerged from the meeting. In addition, we discuss how the ASMB incorporated mentoring, career development, and diversity, equity, and inclusion initiatives. Finally, we reflect on the hybrid scientific conference format and how it will help the ASMB accomplish its mission moving forward.
Read the full report here: https://doi.org/10.1242/bio.059156
Our paper in collaboration with Dr. Bravo-Cordero (Mount Sinai Medical School) demonstrating that "A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy" is now published in Nature Cancer.
Read it here: https://www.nature.com/articles/s43018-021-00291-9
Our paper in collaboration with Dr. Pam Kreeger and Dr. Kristyn Masters (Department of Biomedical Engineering, U. Wisconsin-Madison) and funded by the National Cancer Institute on the "Multi-modal Profiling of the Extracellular Matrix of Human Fallopian Tubes and Serous Tubal Intraepithelial Carcinomas" is now published in the Journal of Histochemistry and Cytochemistry.
Read it here: https://doi.org/10.1369/00221554211061359
Anna will present her work at Cell Bio 2021
Do not miss Anna's virtual poster presentation available on-demand throughout the meeting!
Click here for more information: https://www.ascb.org/cellbio2021/ and read Anna's abstract here: https://www.abstractsonline.com/pp8/#!/10458/presentation/3418
Alexandra will present the latest work of the lab on the development of novel matrisomics methods at the upcoming "Joint Nordic Matrix Biology Meeting" organized by the Finnish Society for Matrix Biology
Alexandra will present the latest work of the lab on the ECM protein SNED1 at the intersection of cancer and development at the "Matrix Festival" organized by the Matrix Biology Society of Australia and New Zealand
Dr. Dharma Pally joins the Naba lab!
We are excited to welcome Dr. Dharma Pally to the Naba lab! Dharma received his PhD from the Indian Institute of Science in Bangalore where he trained in Dr. Bhat's lab. For his postdoctoral training in the lab, Dharma will lead a project aimed at understanding the roles of our favorite ECM protein, SNED1, in breast cancer metastasis. Welcome Dharma!
Fred receives a travel award from the American Society for Matrix Biology to present his work at the 2021 ASMB meeting!
Clarissa receives a travel award from the Honors College to attend #ASMB2021!
Fred and Anna are selected to give short talks at #ASMB2021
Congratulations to Anna Barqué (G5, GEMS) and Fred Lee (G3, MSTP) for being selected to give short talks at the upcoming meeting of he American Society for Matrix Biology (ASMB)! See the program of the meeting here.
The Nab lab takes over Chicago!
Our annual tradition took us this year to downtown Chicago where we enjoyed a round of mini-golf, tacos, and a stroll along the River walk. This year was bitter-sweet as we bid farewell to our fantastic lab manager, Martin Davis, who is heading to medical school! It was also the occasion to celebrate our successes, end the summer term, and enjoy a day off before the new term starts.
The Naba lab is ready for the 2021-2022 academic year!
Attention incoming GEMS students!
The Naba lab has multiple rotation projects in the areas of extracellular matrix biology, cancer biology, and developmental biology available for the 2021-2022 academic year. Project descriptions can be found here.
Students accepted to the GEMS program and interested in rotating in the Naba lab should contact Dr. Naba and provide a CV and brief summary of research interest.
At the invitation of Dr. Steve Badylak, Alexandra will give a talk entitled "10 years of matrisome research: How big data can help advance our understanding of the roles of the ECM in health and disease" at the 11th Biologic Scaffolds for Regenerative Medicine Symposium. More information on this event can be found here.
Congratulations to Clarissa Gomez, currently a sophomore in our lab, for receiving a Liberal Arts and Sciences Undergraduate Research Initiative (LASURI) award for the 2021-2022 academic year!
Alexandra receives the 2020 Philip L. Hawley distinguished faculty award.
This award was established in 1993 by students of the Department of Physiology and Biophysics at UIC to recognize the faculty members who best represent the values held dear by Dr. Philip L. Hawley: supportiveness, enthusiasm, and sincerity. Read more about the award and the list of past recipients here.
In this study in collaboration with Dr. Djalialian's lab (Department of Ophthalmology and Visual Sciences at UIC), we describe an optimized method for fabricating an in-situ thermoresponsive hydrogel from decellularized porcine cornea extracellular matrix and provide a detailed characterization of its structure, thermoresponsive rheological behavior , as well as exploring its protein composition using proteomics. Read the full story here.
The first-ever virtual ball, to be held on April the 10th, will feature games, music, student performances, and the awarding of the first-ever $500 Honors College Advisory Board Scholarship. It also includes faculty networking, with a special appearance from Alexandra!
Congratulations, Clarissa for organizing such a fun and important event for our UIC community!
The Nab lab will be well represented at the spring 2021 meeting of the British Society for Matrix Biology chaired by Stephanie Dakin (Oxford University) on the theme of "Inflammation, Fibrosis, Resolution and the Matrix".
Alexandra will deliver a keynote presentation entitled "10 years of matrisome research: How big data can help advance our understanding of the roles of the ECM in health and disease" and Fred will present a poster describing the development of novel sample preparation protocols to increase identification and coverage of ECM proteins using mass spectrometry.
In this collaborative study led by Tom Van Agtmael, Karen Horsbrugh, and Zameel Cader, we report the development of an approach to extract the cerebrovascular ECM from post-mortem brain tissues and analyze its composition using proteomics. This atlasing effort provides a powerful resource to study the functions of the brain ECM and highlight a specific role for ECM proteins in cerebrovascular diseases. Read the full article published in the Journal of Cerebral Blood Flow & Metabolism, here.
In this study conducted in collaboration with the laboratory of Dr. Sylvie Ricard-Blum (Université Lyon I, France), we employed in-silico and in-vitro approaches to characterize the physico-chemical properties of the novel ECM protein, SNED1, and infer its putative functions. The results of our study are now published in Biochemical Journal and can be found here.
In a new study conducted in collaboration with Dr. Valerio Izzi from the University of Oulu, Finland, we interrogated data from the Pan-Cancer cohort spanning 32 tumor types to evaluate the extent and frequency of mutations affecting post-translational modification sites in matrisome genes and assessed their possible roles on protein functions. The results of our study are now published in Cancers in open access and can be found here.
2016 - 2020 Archives
Publication news! — Dec 17, 2020 5:43:28 PM
Ali and Clarissa receive Undergraduate Research Grants from the Honors College! — Dec 2, 2020 10:27:38 PM
Alexandra is speaking at the Johns Hopkins University's Women's Malignancies Program Seminar Series — Nov 16, 2020 7:23:28 PM
Anna is awarded a Cornerstone Grant from the Histochemical Society! — Sep 18, 2020 7:18:48 PM
The Naba lab receives a pilot project research grant from the University of Illinois Cancer Center — Sep 2, 2020 10:42:18 PM
New publication: Pan-Cancer Analysis of the Genomic Alterations and Mutations of the Matrisome — Jul 24, 2020 5:32:24 PM
Anna is presenting her work at the 2020 virtual meeting of the Society for Developmental Biology — Jul 16, 2020 7:39:13 PM
Anna receives an Award for Graduate Research! — Apr 21, 2020 2:49:39 PM
New publication: The liver matrisome: looking beyond collagens — Apr 19, 2020 9:07:54 PM
Clarissa is selected to participate in the 2020 Summer Research Opportunities Program! — Apr 13, 2020 7:39:29 PM
Anna receives a Provost’s Graduate Research Award! — Dec 9, 2019 6:04:52 AM
Alexandra is presenting at the 2019 ASCB/EMBO meeting — Dec 9, 2019 5:58:22 AM
Alexandra will deliver the keynote lecture at the 2019 meeting of the Irish Society for Matrix Biology — Nov 13, 2019 10:28:55 PM
New publication: In-silico definition of the Drosophila melanogaster matrisome — Nov 11, 2019 1:10:11 AM
Isra receives an Undergraduate Research Grant from the Honors College — Nov 1, 2019 4:29:06 PM
Alexandra is invited to speak at the University of Copenhagen — Sep 30, 2019 4:59:10 PM
Ali receives a Chancellor’s Undergraduate Research Award! — Sep 3, 2019 7:47:37 PM
New Publication: Exploring the extracellular matrix in health and disease using proteomics — Aug 30, 2019 2:17:47 AM
New Publication: In-silico definition of the Drosophila melanogaster matrisome — Aug 5, 2019 12:46:38 PM
The Naba Lab is part of a collaborative effort awarded a 5-year NIH grant to study scleroderma — Jun 24, 2019 11:50:49 PM
Isra receives a LASURI award! — Apr 16, 2019 7:45:41 PM
Alexandra is speaking this week at the 2019 Gordon Research Conference on Cartilage — Mar 18, 2019 12:44:31 AM
Alexandra is appointed to the council of the ISMB for the Americas — Mar 14, 2019 7:32:50 PM
Alexandra is speaking today at the Department of Bioengineering seminar series — Mar 1, 2019 12:55:09 PM
Congratulations Kyleen! — Jan 6, 2019 9:55:29 PM
New Publication: MatrixDB: integration of new data with a focus on glycosaminoglycan interactions. — Nov 4, 2018 11:29:32 PM
Kyleen, Isra and Morgan receive Honors College Undergraduate Research Grants! — Oct 30, 2018 10:15:08 AM
Alexandra is speaking this week at Rush University. — Oct 26, 2018 2:36:11 PM
The Naba Lab receives a Catalyst Award from the Chicago Biomedical Consortium to study scleroderma — Sep 25, 2018 7:14:48 PM
Alexandra is lecturing at the 2018 FEBS Advanced Course on the Extracellular Matrix in Patras, Greece. — Sep 17, 2018 2:17:50 AM
Alexandra is featured in the September issue of Matrix Biology — Sep 11, 2018 3:37:44 AM
Alexandra is receiving the Rupert Timpl award at the 2018 Matrix Biology Europe meeting — Jul 20, 2018 2:52:06 PM
New Publication: The cancer matrisome: from comprehensive characterization to biomarker discovery — Jul 14, 2018 12:24:29 PM
Alexandra receives the 2018 Rising Star award from the Department of Physiology and Biophysics! — May 10, 2018 11:49:52 PM
Morgan and Kyleen receive LASURI awards! — May 2, 2018 1:33:10 AM
Alexandra is giving a talk at the 2018 meeting of the American Association for Cancer Research — Apr 16, 2018 12:04:46 PM
New Publication: Extracellular matrix in lung development, homeostasis and disease. — Mar 24, 2018 11:00:47 PM
Alexandra is lecturing at the 8th Hong Kong University - Pasteur Cell Biology course — Mar 13, 2018 9:33:03 PM
Alexandra is speaking this week at the Lerner Research Institute at Cleveland Clinic. — Feb 28, 2018 1:49:06 AM
Alexandra receives the 2018 ISMB Rupert Timpl Award — Feb 18, 2018 5:06:58 PM
Alexandra receives the 2018 ASMB Junior Investigator Award — Jan 30, 2018 8:03:32 PM
Alexandra is speaking this week at UC Denver. — Jan 9, 2018 10:30:49 PM
Alexandra is speaking at this month's Chicago Mass Spec Discussion Group meeting — Dec 11, 2017 2:03:35 PM
Lexie receives a Chancellor's Graduate Research Award! — Dec 5, 2017 2:21:45 PM
Alexandra is speaking at this week's Postgraduate in Life Science seminar series at the CICESE. — Nov 29, 2017 12:54:27 PM
Alexandra is speaking at this week's Endocrinology Division seminar series — Nov 8, 2017 7:48:35 PM
Kyleen and Morgan receive Honors College Undergraduate Research Grants! — Oct 26, 2017 9:10:26 PM
Alexandra is speaking at the annual symposium of the Wellcome Trust Center for Cell-Matrix Research — Oct 9, 2017 9:06:47 AM
Alexandra is speaking at this week's Cardiovascular Division seminar series at King's College London — Oct 5, 2017 6:55:46 PM
Lexie presents her first poster as graduate student at the GEMS Research Symposium! — Oct 5, 2017 6:48:16 PM
Yash receives a Chancellor’s Undergraduate Research Award! — Oct 5, 2017 6:40:46 PM
New bioinformartic tools for matrisome analysis! — Jul 27, 2017 9:04:35 PM
Alexandra is speaking at the upcoming Gordon Research Conference on Collagens. — Jul 13, 2017 3:20:51 AM
Publication: Characterization of the ECM of normal and diseased tissues using proteomics. — Jul 10, 2017 6:41:22 PM
Alexandra is named a fellow of UIC Honors College. — May 23, 2017 3:44:25 PM
Publication: Proteomic characterization of human multiple myeloma bone marrow extracellular matrix. — Apr 20, 2017 4:28:06 PM
Read Alexandra's interview in the spring 2017 issue of the Matrix Newlsetter — Apr 3, 2017 4:46:53 PM
Publication: Comprehensive proteomic characterization of stem-cell-derived extracellular matrices — Mar 14, 2017 11:26:26 AM
Alexandra's research profile on YouTube! — Feb 13, 2017 3:03:11 PM
Alexandra is elected to the council of the American Society for Matrix Biology — Jan 17, 2017 1:00:14 PM
Alexandra joins the editorial board of the Journal of Immunology and Regenerative Medicine — Jan 2, 2017 9:11:20 AM
Alexandra is speaking at this week's UI Cancer Center Breast Cancer Seminar — Dec 15, 2016 1:22:57 PM
The Naba Lab is featured in the fall 2016 newsletter of the International Society for Matrix Biology! — Nov 18, 2016 2:17:32 PM
Alexandra is chairing the Tumor Microenvironment session at the upcoming ASMB meeting — Nov 11, 2016 10:29:08 PM
MatrisomeDB 2.0 is now live! — Nov 9, 2016 3:03:57 PM
Alexandra will be speaking at this week's Regenerative Sciences Seminar Series — Nov 8, 2016 12:40:13 AM
Alexandra named associate member of U of IL Cancer Center — Oct 31, 2016 2:19:28 PM
Ready to move in! — Aug 13, 2016 1:00:03 AM