Publication: Quantitative proteomic profiling of the ECM of pancreatic islets during the angiogenic switch and insulinoma progression

Our latest paper is out in Scientific Reports! In this study, we used quantitative proteomics to profile the composition of the ECM, or the matrisome, of pancreatic islets in a model of insulinoma characterized by a precisely timed angiogenic switch. The angiogenic switch being a common feature of solid tumors, we propose that some of the proteins identified represent potential anti-angiogenic targets. The article is available in open access here.