New publication: In-silico characterization of the Caenorhabditis elegans matrisome and proposal of a novel collagen classification.

Our paper in collaboration with Jan Gebauer and Collin Ewald is published in open access in Matrix Biology Plus.

In this paper, we used a bioinformatic approach combining gene orthology and protein structure analysis and an extensive curation of the literature to define the C. elegans matrisome. Similar to the human genome, we found that ~4% of the C. elegans genome encodes matrisome proteins. To facilitate the use of our lists and classification by the scientific community, we developed an automated annotation tool to identify ECM components in large datasets. We also established a novel database of all C. elegans collagens: CeColDB. Read our article here.